THE DEFINITIVE GUIDE TO FASTGAS

The final proposed mechanism of RBC vasodilation while in the existence of nitrite may be the reduction of nitrite to NO by Hb. Brooks 1st researched the nitrite Hb conversation in 1937 and this function was afterwards extended by Doyle in 1981 (Brooks, 1937; Doyle et al., 1981). Nitrite reacts with deoxygenated Hb to form metHb and NO (Brooks, 193